Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9974 CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Chronic: Rinse mouth with water (only if the person is conscious). System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day none Water, Foam, Alcohol resistant foam, ABC-powder Water jet Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2) In … A combination of these processes should be important. Colorless needles, white lumps, or pellets with an irritating, choking odor. May cause digestive tract Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride. Maleic acid 110-16-7 >95 4. CDC twenty four seven. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Causes redness and pain. Stir the mixture for 10 min. Appearance: white lumps. Immediate medical attention is required. Eye: "Maleic Anhydride, Maleic Acid, and Fumaric Acid." Product name : Maleic Anhydride CAS-No. Repeated SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. May cause conjunctivitis. Inhalation: : 607-096-00-9 CAS-No. double vision, and "halo" vision. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Product identifier Identification number Name of the substance Maleic anhydride 607-096-00-9 (Index number) Registration number 01-2119472428-31 Synonyms MAN Issue date 07-March-2019 Version number 01 Revision date-Supersedes date-1.2. Remove victim to fresh Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances 1.3 Details of the supplier of the safety data sheet Danger! reaction, which becomes evident upon re-exposure to this material. Anhydrides. Causes respiratory You will be subject to the destination website's privacy policy when you follow the link. EC -No. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. safety hazards of Maleic Acid to potentially exposed workers. Show this safety data sheet to the doctor in attendance. NCI [1974]. Target Organs: Lungs, respiratory system, eyes, Moisture sensitive. A poison by intravenous route. [Note: Reacts slowly with water (hydrolyzes) to form maleic acid. The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Symptoms and effects are not known to date. May cause allergic skin and respiratory reaction. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. (2) Conversion Factors: The odour warning when the exposure limit value is exceeded is insufficient. 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) Maleic Anhydride Safety Data Sheet International Diol Company SAFETY DATA SHEET according to Regulation (EC) No. First-aid measures General Advice Show this safety data sheet to the doctor in attendance. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Causes skin burns. May cause blistering of the skin. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. 6. Wash out mouth with water. Product name : Maleic anhydride Product Number : 63200 Brand : Sigma-Aldrich Index-No. Exposure to high fume concentrations cause photophobia, FIRST AID MEASURES General advice Consult a physician. Hazard classification & labelling Hazard classification and labelling. Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. Maleic Anhydride 95 - 100% 108-31-6 Get medical attention immediately. Evaporate the chloroform in a hood. Recrystallize the maleic anhydride from toluene. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … Harmful if swallowed. Common Name Maleic Anhydride Synonym(s) 2,5Furandione Formula C 4 H 2 O 3 CAS Number 108316 COMPONENT CAS NUMBER CONCENTRATION Maleic Anhydride 108316 ≤ Section 4. Interagency Collaborative Group on Environmental Carcinogens. Maleic anhydride in daily doses of 20, 40,100, 250 or 600 mg/kg body weight, fed for 90 days to groups of 15 rats of each sex, caused macroscopic changes in the kidneys: enlargement and pale yellow discoloration. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. MCA [1974]. Histological examination revealed nephrosis which increased in severity with the dose above 100 mg/kg. Immediate medical attention is required. If inhaled If breathed in, move person into fresh air. Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. skin. pain. ], inhalation, ingestion, skin and/or eye contact, irritation nose, upper respiratory system; conjunctivitis; photophobia (abnormal visual intolerance to light), double vision; bronchial asthma; dermatitis, Centers for Disease Control and Prevention. 5. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. May cause asthmatic attacks due to allergic sensitization of the Risk Statements: 36/37/38 R36/37/38:Irritating to eyes, respiratory system and skin. ... Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. Causes redness and When heated to decomposition it emits acrid smoke and irritating vapors. exposure may cause allergic respiratory reaction (asthma). Potential Health Effects SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Inhalation of high concentrations may cause pulmonary edema. cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride Colorless needles, white lumps, or pellets with an irritating, choking odor. irritation with nausea, vomiting, and diarrhea. Harmful if swallowed. Maleic anhydride TWA: 0.01 mg/m 3(Vacated) TWA: 0.25 ppm (Vacated) TWA: 1 mg/m3 TWA: 0.25 ppm TWA: 1 mg/m3 IDLH: 10 mg/m TWA: 0.25 ppm TWA: 1 mg/m3 TWA: 0.01 ppm Legend ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and … 108 -31 -6 203 -571 -6 607 -096 -00 -9 - 4. May cause skin sensitization, an allergic Wear safety goggles or eye protection in combination with breathing protection if powder. Safety Data Sheet 24 hour Emergency Response No. Ingestion: Polynt Group produces a great variety of anhydrides, but the most important ones are: Phthalic Anhydrides, Maleic Anhydride, Trimellitic Anhydride Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. Dissolve the residue in a minimal amount of chloroform. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. Memorandum. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. Skin: Environmental: Maleic anhydride's fate in soil is unknown. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. : 108-31-6 Molecular Weight: 98.06 Chemical Formula: C4H2O3 Company: ADDTEK CHEMICAL SHANGHAI CO LTD TEL: +86 21 63352916 FAX: +86 21 51010033EXT8839 +86-532-8027466 SECTION 1: PRODUCT AND COMPANY IDENTIFICATION ... Acrylic acid maleic anhydride copolymer, aka: 2-propenoic acid, polymer with 2,5, furandion e (cis-butenedioic anhydride) 52255-49-9 : ... Acrylic Acid Maleic … respiratory tract. Environmental: Maleic anhydride's fate in soil is unknown. Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues National Cancer Institute, June 17, 1974. Causes gastrointestinal tract burns. Corrosive. Prolonged or repeated skin contact may cause dermatitis. Maleic anhydride is used in the formulation of resins. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Causes severe eye and skin irritation with possible Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Combustible Solid, but may be difficult to ignite. Index -No. Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. Washington, DC: Manufacturing Chemists Association, p. 1-13. Product Identification Synonyms: cis-Butenedioic anhydride; 2,5-furandione; toxilic anhydride CAS No. Causes chemical burns to the respiratory tract. tract irritation and possible burns. Move out of dangerous area. If not breathing, give artificial respiration. (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). Maleic anhydride CAS -No. Product Safety Assessment: Maleic Anhydride Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for occupational exposure to Maleic Anhydride exists during manufacture, at transloading, storage and staging areas, and during mixing and sampling operations in the manufacture of other products. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Do NOT induce vomiting. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Safety Statements :26-36/37/39 Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F Maleic Anhydride Flinn Scientific, Inc. P.O. Maleic anhydride, polymers Safety Profile. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Causes eye burns. burns. Consult a physician. Chemical safety data sheet sd-88: properties and essential information for safe handling and use of maleic anhydride. Chem., 1979, 179, C19], and is considered an excellent dieneophile for Diels-Alder reactions [Felthouse, Timothy R. et al. Reproductive Toxicity: No data available Reproductive toxicity - Rat - Oral Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. 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